Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24036413 | 0.79 | MEN1 (0.43) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL11424096 | 0.77 | FFAR1 (0.45) | MEN1KMT2AKDM4EPOLB | |
| SCHEMBL1750044 | 0.72 | — | — | |
| SCHEMBL4347156 | 0.71 | EGFR (0.40) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL4358645 | 0.71 | EGFR (0.45) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4347704 | 0.70 | EGFR (0.37) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9377008 | 0.69 | — | — | |
| SCHEMBL14308851 | 0.69 | — | — | |
| SCHEMBL19419957 | 0.68 | MEN1 (0.67) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL28675543 | 0.68 | MEN1 (0.67) | MEN1KMT2AHTTMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730838-B2 | Green preparation method for quinoline compounds | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2020-08-04 | — | — | US | disclosed |
| US-20200079737-A1 | GREEN PREPARATION METHOD FOR QUINOLINE COMPOUNDS | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2020-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079737-A1 | GREEN PREPARATION METHOD FOR QUINOLINE COMPOUNDS | NQO1, TYR, ABCG2 | MEN1 2631/4885KMT2A 1710/4885HTT 439/4885 |
| US-10730838-B2 | Green preparation method for quinoline compounds | NQO1, TYR, ABCG2 | MEN1 2631/4885KMT2A 1710/4885HTT 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.