Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18109936 | 0.86 | CA12 (0.50) | CA12CA1CA2CA9KCNQ4 | |
| SCHEMBL18109934 | 0.81 | PLK1 (0.50) | S1PR4S1PR1S1PR3S1PR5PLK1 | |
| SCHEMBL18109931 | 0.81 | CA12 (0.42) | CA12CA1CA2CA9KCNQ4 | |
| Iodide SCHEMBL16742380 | 0.77 | CHRNA7 (0.46) | CA12CA1CA2CA9 | |
| SCHEMBL23093001 | 0.76 | KCNQ4 (0.39) | CA12CA1CA2KCNQ4KCNQ5 | |
| SCHEMBL21464183 | 0.74 | CA12 (0.46) | CA12CA1CA2CA9 | |
| SCHEMBL18109928 | 0.73 | CHRNA7 (0.40) | CA12CA1CA2CA9 | |
| SCHEMBL15888157 | 0.73 | MEN1 (0.47) | CA12CA1CA2CA9THRA | |
| SCHEMBL24675687 | 0.72 | CA12 (0.46) | CA12CA1CA2CA9 | |
| SCHEMBL24674856 | 0.72 | CA12 (0.46) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071582-B1 | MITOCHONDRIA-TARGETED DICARBONYL SEQUESTERING COMPOUNDS | RES & INNOVATION UK (GB) | 2020-04-29 | — | — | EP | disclosed |
| EP-3623375-A1 | MITOCHONDRIA-TARGETED DICARBONYL SEQUESTERING COMPOUNDS | United Kingdom Research and Innovation (GB) | 2020-03-18 | — | — | EP | disclosed |