SCHEMBL21799647

SCHEMBL21799647

CC(Nc1ccccc1N)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.41
MAPT P10636 6/20 0.41
GAA P10253 5/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
SMN1; SMN2 Q16637 3/20 0.38
ALOX15 P16050 2/20 0.38
TP53 P04637 1/20 0.38
APP P05067 1/20 0.38
HPGD P15428 1/20 0.38
SNCA P37840 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922792 1.00 PLK1 (0.41) PLK1MAPTGAAKDM4EALDH1A1
SCHEMBL21799728 0.79 MAPT (0.43) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL29922524 0.79 MAPT (0.43) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL29922761 0.79 MAPT (0.46) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL22150361 0.79 MAPT (0.46) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL1022329 0.79 MAPT (0.46) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL15430619 0.77 MAPT (0.45) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL13813004 0.76 PLK1 (0.41) PLK1MAPTGAAALDH1A1MEN1
SCHEMBL9297138 0.75 MAPT (0.43) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL14467078 0.75 MAPT (0.43) MAPTGAAKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
CN-110603273-B Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2022-10-14 CN disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed