Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 17/20 | 1.00 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.61 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.61 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152856 | 0.89 | GRIA2 (0.80) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL2152080 | 0.89 | GRIA2 (1.00) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL2152051 | 0.89 | GRIA2 (1.00) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL2152720 | 0.88 | GRIA2 (1.00) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL2183133 | 0.88 | GRIA2 (0.79) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL2153213 | 0.88 | GRIA2 (1.00) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL1974811 | 0.88 | GRIA2 (0.78) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL2161138 | 0.86 | GRIA2 (0.82) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL2183722 | 0.85 | GRIA2 (1.00) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL1981280 | 0.83 | GRIA2 (0.71) | GRIA2GRIA1GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083265-A1 | NOVEL DERIVATIVES OF CYCLOPROPYLATED BENZOTHIADIAZINES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |