⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863181 | 1.00 | — | — | |
| SCHEMBL1864723 | 1.00 | — | — | |
| SCHEMBL5170595 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL1144431 | 0.97 | — | — | |
| SCHEMBL9359194 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL2535651 | 0.97 | — | — | |
| SCHEMBL9122289 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL11067279 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL21222731 | 0.97 | — | — | |
| SCHEMBL11062282 | 0.97 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1803 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024114814-A1 | JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | ONQUALITY PHARMACEUTICALS CHINA LTD (CN) | 2024-06-06 | — | — | WO | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| CN-117983302-A | Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof | 华东理工大学 | 2024-05-07 | — | — | CN | claimed |
| WO-2023194964-A1 | FUSED PYRIDAZINE DERIVATIVES AS NLRP3 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-12 | — | — | WO | claimed |
| CN-116554079-A | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116284536-A | Copolymer and binder for lithium battery | 上海华谊三爱富新材料有限公司 | 2023-06-23 | — | — | CN | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| US-20230138795-A1 | DOPAMINE-B-HYDROXYLASE INHIBITORS | BIAL PORTELA & CA SA (PT) | 2023-05-04 | — | — | US | claimed |
| US-20220396579-A1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2022-12-15 | — | — | US | claimed |
| US-11186583-B2 | 5-alkylthio-7-[(4-arylbenzyl)amino]-1(2)H-pyrazolo[4,3-d]pyrimidines for treatment of lymphoma | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2021-11-30 | — | — | US | claimed |
| EP-0434080-A1 | Derivatives of N-hals-substituted amic acid hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | claimed |
| EP-0434608-A1 | Stabilized organic material | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | claimed |
| US-4873346-A | BRONCHODILATORS, TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1989-10-10 | — | — | US | claimed |
| EP-0165209-B1 | O,P-BIFUNCTIONALISED, O'-SUBSTITUTED PHENOLS | CIBA-GEIGY AG (CH) | 1989-07-19 | — | — | EP | claimed |
| US-4759862-A | O,p-bifunctionalized o'-substituted phenols | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | claimed |
| EP-0165209-A2 | o,p-Bifunctionalised, o'-substituted phenols | CIBA-GEIGY AG (CH) | 1985-12-18 | — | — | EP | claimed |
| US-4281075-A | REACTIVE HYDROXYL-FUNCTIONALITY AND AMINE-ALDEHYDE CROSSLINKING AGENT | FORD MOTOR COMPANY (US) | 1981-07-28 | — | — | US | claimed |
| EP-0006693-A1 | N-substituted trialkylstannylhydrocarbylcarboxylic acid hydrazides, methods of their preparation and insecticide compositions containing them | UNIROYAL, INC. (US) | 1980-01-09 | — | — | EP | claimed |
| US-4178382-A | INSECTICIDE FOR COTTON | UNIROYAL, INC. (US) | 1979-12-11 | — | — | US | claimed |
| US-3968102-A | VASODILATOR, ANTICOAGULANT | KOHJIN CO., LTD. (JA) | 1976-07-06 | — | — | US | claimed |