Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147824 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 | |
| SCHEMBL123159 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 | |
| SCHEMBL5029031 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 | |
| SCHEMBL15913813 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 | |
| SCHEMBL3738398 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 | |
| SCHEMBL1147818 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 | |
| SCHEMBL9224709 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 | |
| SCHEMBL10823975 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 | |
| SCHEMBL2386979 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 | |
| SCHEMBL10437388 | 1.00 | CETP (0.48) | CETPCYP4F2CYP4A11SPHK1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596053-B1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | ORGANOVO INC (US) | 2023-08-16 | — | — | EP | disclosed |
| EP-3852736-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | Metacrine, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061118-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020061116-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020061117-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |