Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 15/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21807899 | 0.87 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL21807954 | 0.86 | PIK3CD (0.45) | PIK3CD | |
| SCHEMBL31051490 | 0.86 | PIK3CD (0.45) | PIK3CD | |
| SCHEMBL21807909 | 0.84 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL21807912 | 0.74 | OGA (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL21807906 | 0.73 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL31051491 | 0.73 | PIK3CD (0.46) | HCRTR1HCRTR2PIK3CD | |
| SCHEMBL31051476 | 0.73 | PIK3CD (0.46) | HCRTR1HCRTR2PIK3CD | |
| SCHEMBL31128769 | 0.73 | OGA (0.45) | — | |
| SCHEMBL21807952 | 0.71 | OGA (0.37) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853226-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061150-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-03-26 | — | — | WO | disclosed |