Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 6/20 | 0.44 |
| ▸ | OPRM1 known ✓ | P35372 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 8/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27702816 | 0.96 | SLC6A4 (0.42) | SLC6A4MAPK1LMNAKDM4ESMN1; SMN2 | |
| Acetic Acid SCHEMBL27702815 | 0.96 | SLC6A4 (0.42) | SLC6A4MAPK1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1362860 | 0.95 | SLC6A4 (0.40) | SLC6A4MAPK1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL29414619 | 0.95 | BCL2 (0.42) | SLC6A4MAPK1LMNASMN1; SMN2BCL2 | |
| SCHEMBL679 | 0.95 | BCL2 (0.42) | SLC6A4MAPK1LMNASMN1; SMN2BCL2 | |
| SCHEMBL907577 | 0.95 | BCL2 (0.42) | SLC6A4MAPK1LMNASMN1; SMN2BCL2 | |
| SCHEMBL29414628 | 0.95 | BCL2 (0.42) | SLC6A4MAPK1LMNASMN1; SMN2BCL2 | |
| SCHEMBL907571 | 0.95 | BCL2 (0.42) | SLC6A4MAPK1LMNASMN1; SMN2BCL2 | |
| Pivalate SCHEMBL27604130 | 0.94 | SLC6A4 (0.40) | SLC6A4MAPK1LMNAKDM4ESMN1; SMN2 | |
| Pivalate SCHEMBL6237077 | 0.94 | SLC6A4 (0.40) | SLC6A4MAPK1LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020060011-A1 | NOVEL PREPARATION METHOD FOR CITALOPRAM AND ESCITALOPRAM USING CARBONATES | (주)유케이케미팜 | 2020-03-26 | — | — | WO | disclosed |