Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746609 | 0.90 | PTPN11 (0.43) | PDPK1PTPN11PIK3C3BRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1487920 | 0.89 | PTPN11 (0.42) | PDPK1PTPN11PIK3C3BRD4ALDH1A1 | |
| SCHEMBL2179100 | 0.82 | BRD4 (0.54) | PDPK1PTPN11PIK3C3BRD4P2RY12 | |
| SCHEMBL12410748 | 0.81 | PTPN11 (0.43) | PTPN11JMJD6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1487554 | 0.78 | BRD4 (0.42) | PTPN11PIK3C3BRD4ALDH1A1HSD17B10 | |
| SCHEMBL12410738 | 0.78 | JMJD6 (0.37) | PTPN11P2RY12JMJD6NPC1RAB9A | |
| SCHEMBL13746240 | 0.77 | PTPN11 (0.53) | PDPK1PTPN11PIK3C3BRD4GBA1 | |
| SCHEMBL8321386 | 0.77 | BRD4 (0.44) | PDPK1PTPN11BRD4ALDH1A1HSD17B10 | |
| SCHEMBL2753498 | 0.77 | PDPK1 (0.49) | PDPK1PTPN11BRD4 | |
| SCHEMBL13669264 | 0.77 | PTPN11 (0.50) | PDPK1PTPN11NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166173-A1 | 3,5-DISUBSTUTUTED 1H-PYRROLO [2,3-B] PYRIDINES AS JNK INHIBITORS | EISAI CO., LTD. (JP) | 2011-07-07 | — | — | US | disclosed |
| EP-1720871-B1 | 3,5-DISUBSTITUTED 1H-PYRROLO [2,3-B] PYRIDINES AS JNK INHIBITORS | EISAI R&D MAN CO LTD (JP) | 2010-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166173-A1 | 3,5-DISUBSTUTUTED 1H-PYRROLO [2,3-B] PYRIDINES AS JNK INHIBITORS | API5, CDK5, MAPKAPK5 | PDPK1 85/4885PTPN11 894/4885PIK3C3 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.