Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.44 |
| ▸ | ABCC2 | Q92887 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.44 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21812732 | 0.92 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL21812928 | 0.90 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL16994083 | 0.85 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL21813211 | 0.85 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL21813212 | 0.85 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL21813042 | 0.85 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL21812881 | 0.84 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL21812879 | 0.84 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL21813081 | 0.84 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL21812796 | 0.84 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736885-B1 | QUINOLINE-, QUINOXALINE OR BENZOTHIAZOLE BASED CYSTEINYL LEUKOTRIENE ANTAGONISTS (LTC4) | SUN PHARMA ADVANCED RES CO LTD (IN) | 2020-03-25 | — | — | EP | disclosed |