Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 10/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 10/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304608 | 1.00 | CARM1 (0.51) | CARM1PRMT6PRMT1PRMT5WDR77 | |
| SCHEMBL304374 | 0.87 | CARM1 (0.50) | CARM1PRMT6PRMT1PRMT5WDR77 | |
| SCHEMBL21819915 | 0.87 | CARM1 (0.50) | CARM1PRMT6PRMT1PRMT5WDR77 | |
| SCHEMBL303279 | 0.86 | CARM1 (0.49) | CARM1PRMT6PRMT1PRMT5WDR77 | |
| SCHEMBL21819922 | 0.86 | CARM1 (0.49) | CARM1PRMT6PRMT1PRMT5WDR77 | |
| SCHEMBL1921436 | 0.78 | PTGDR2 (0.36) | CARM1 | |
| SCHEMBL1921985 | 0.73 | JAK2 (0.39) | CARM1 | |
| SCHEMBL27935518 | 0.73 | CARM1 (0.43) | CARM1PRMT5WDR77 | |
| SCHEMBL2032269 | 0.72 | CARM1 (0.35) | CARM1 | |
| SCHEMBL303798 | 0.72 | CARM1 (0.39) | CARM1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328871-B1 | HEDGEHOG PATHWAY MODULATORS | NOVARTIS AG (CH) | 2020-04-01 | — | — | EP | claimed |