SCHEMBL21820104

SCHEMBL21820104

[2H]C(O)(O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995765 0.78 CETP (0.35)
SCHEMBL31078207 0.75
SCHEMBL1314654 0.73
SCHEMBL27246 0.70
SCHEMBL28370516 0.70
SCHEMBL26092 0.67
SCHEMBL30703063 0.67
SCHEMBL18422910 0.67 CETP (0.39)
SCHEMBL2852867 0.67 CETP (0.39)
SCHEMBL18422707 0.67 CETP (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021102221-A1 DEUTERATED ANALOGS OF AN IDH1 INHIBITOR AGIOS PHARMACEUTICALS, INC. (US) 2021-05-27 WO disclosed
US-20200085832-A1 DEUTERATED ANALOGS OF AN ORGANIC COMPOUND SERVIER PHARMACEUTICALS LLC 2020-03-19 US disclosed