Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.49 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.49 |
| ▸ | KLRK1 | P26718 | 3/20 | 0.47 |
| ▸ | MICA | Q29983 | 3/20 | 0.47 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283810 | 0.93 | KLRK1 (0.53) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL19283862 | 0.93 | KLRK1 (0.52) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL21821288 | 0.93 | KLRK1 (0.52) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL21821304 | 0.92 | HRH4 (0.49) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL19283725 | 0.91 | ITGA5 (0.48) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL19283627 | 0.90 | ITGA5 (0.46) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL21821297 | 0.90 | TACR1 (0.48) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL21821293 | 0.89 | ITGA5 (0.46) | ITGA5ITGB6ITGB8KLRK1MICA | |
| Iodide SCHEMBL19283626 | 0.88 | ITGA5 (0.46) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL21821321 | 0.87 | ITGA5 (0.44) | ITGA5ITGB6ITGB8KLRK1MICA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419973-B1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2020-04-08 | — | — | EP | claimed |