Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.56 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822498 | 0.82 | F10 (0.57) | F10F2 | |
| SCHEMBL21822172 | 0.77 | F10 (0.57) | F10F2 | |
| SCHEMBL25016310 | 0.77 | F10 (0.57) | F10F2 | |
| SCHEMBL25016830 | 0.74 | F10 (0.53) | F10F2 | |
| SCHEMBL25016089 | 0.74 | F10 (0.52) | F10F2 | |
| SCHEMBL25016742 | 0.73 | F10 (0.54) | F10F2 | |
| SCHEMBL25015989 | 0.73 | F2 (0.50) | F10F2 | |
| SCHEMBL31689639 | 0.73 | F10 (0.53) | F10F2 | |
| SCHEMBL25017861 | 0.72 | F10 (0.45) | F10F2 | |
| SCHEMBL25016794 | 0.72 | F10 (0.47) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860636-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | Disc Medicine, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020072580-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. (US) | 2020-04-09 | — | — | WO | disclosed |