SCHEMBL2182387

SCHEMBL2182387

CCCC[C@H]([C]=O)NC(=O)[C@@H](N)CCCC

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 12/20 0.57
DPP9 Q86TI2 9/20 0.57
DPP8 Q6V1X1 9/20 0.57
DPP4 P27487 6/20 0.57
SLC15A1 P46059 1/20 0.53
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
RRM1 P23921 1/20 0.41
METAP1 P53582 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
CHEK1 O14757 1/20 0.38
ERAP2 Q6P179 1/20 0.37
LNPEP Q9UIQ6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7613327 0.95 DPP7 (0.58) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL10520841 0.92 DPP7 (0.62) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL8721584 0.92 DPP7 (0.58) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL2182733 0.86 DPP7 (0.51) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL9797628 0.86 DPP7 (0.50) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL8991404 0.86 DPP7 (0.50) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL8495681 0.84 DPP7 (0.56) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL7751944 0.83 DPP7 (0.50) DPP7DPP9DPP8DPP4GNAI3
SCHEMBL7751947 0.83 DPP7 (0.50) DPP7DPP9DPP8DPP4GNAI3
SCHEMBL2193195 0.81 NPY4R (0.48) DPP7DPP9DPP8DPP4SLC15A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NGLY1, CD44, IAPP DPP7 450/4885DPP9 996/4885DPP8 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.