Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.45 |
| ▸ | ACACA | Q13085 | 3/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2939683 | 1.00 | ACACB (0.45) | ACACBACACACACNA1ICACNA1GCACNA1H | |
| SCHEMBL2939680 | 1.00 | ACACB (0.45) | ACACBACACACACNA1ICACNA1GCACNA1H | |
| SCHEMBL30703525 | 0.81 | CACNA1I (0.35) | ACACBCACNA1ICACNA1GCACNA1HCYP4F2 | |
| SCHEMBL28781905 | 0.81 | CACNA1I (0.47) | CACNA1ICACNA1GCACNA1H | |
| SCHEMBL1064478 | 0.81 | CACNA1I (0.47) | CACNA1ICACNA1GCACNA1H | |
| SCHEMBL28781906 | 0.81 | CACNA1I (0.47) | CACNA1ICACNA1GCACNA1H | |
| SCHEMBL1063142 | 0.81 | CACNA1I (0.51) | ACACBCACNA1ICACNA1GCACNA1H | |
| SCHEMBL2134252 | 0.80 | CACNA1I (0.34) | ACACBCACNA1ICACNA1GCACNA1H | |
| SCHEMBL2134255 | 0.80 | CACNA1I (0.34) | ACACBCACNA1ICACNA1GCACNA1H | |
| SCHEMBL15351146 | 0.79 | CNR2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632899-A1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RaQualia Pharma Inc. (JP) | 2020-04-08 | — | — | EP | disclosed |
| CN-102448937-A | Aryl Substituted Carboxamide Derivatives As Calcium Or Sodium Channel Blockers | RAQUALIA PHARMA INC | 2012-05-09 | — | — | CN | disclosed |