Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.65 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.62 |
| ▸ | FLT3 | P36888 | 5/20 | 0.62 |
| ▸ | KDR | P35968 | 2/20 | 0.62 |
| ▸ | KIT | P10721 | 2/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.62 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21824006 | 1.00 | CSF1R (0.65) | CSF1RPDGFRBPDGFRAFLT3KDR | |
| SCHEMBL30673539 | 1.00 | CSF1R (0.65) | CSF1RPDGFRBPDGFRAFLT3KDR | |
| SCHEMBL21824024 | 0.86 | CSF1R (0.67) | CSF1RPDGFRBPDGFRAFLT3KDR | |
| SCHEMBL30673544 | 0.86 | CSF1R (0.67) | CSF1RPDGFRBPDGFRAFLT3KDR | |
| SCHEMBL21824035 | 0.86 | CSF1R (0.66) | CSF1RPDGFRBPDGFRAFLT3KDR | |
| SCHEMBL21824020 | 0.83 | CSF1R (0.68) | CSF1RPDGFRBPDGFRAFLT3KDR | |
| SCHEMBL21851723 | 0.82 | CSF1R (0.64) | CSF1RPDGFRBPDGFRAFLT3KDR | |
| SCHEMBL21824031 | 0.82 | CSF1R (0.64) | CSF1RPDGFRBPDGFRAFLT3KDR | |
| SCHEMBL21824034 | 0.81 | CSF1R (0.69) | CSF1RPDGFRBPDGFRAFLT3KDR | |
| SCHEMBL31741155 | 0.81 | CSF1R (0.78) | CSF1RPDGFRBPDGFRAFLT3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632906-B1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | ABBISKO THERAPEUTICS CO LTD (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-3632906-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |