Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.39 |
| ▸ | CSF1R | P07333 | 14/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 5/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30673536 | 1.00 | MDM2 (0.39) | MDM2CSF1RPDGFRAIRAK4FLT3 | |
| SCHEMBL21824002 | 0.95 | CSF1R (0.36) | MDM2CSF1RPDGFRAIRAK4FLT3 | |
| SCHEMBL21824017 | 0.86 | CSF1R (0.36) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL30673545 | 0.86 | CSF1R (0.36) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL21824042 | 0.85 | CSF1R (0.37) | MDM2CSF1RPDGFRAIRAK4FLT3 | |
| SCHEMBL30673542 | 0.85 | CSF1R (0.37) | MDM2CSF1RPDGFRAIRAK4FLT3 | |
| SCHEMBL21824018 | 0.83 | CSF1R (0.58) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL21823994 | 0.81 | CSF1R (0.32) | CSF1RPDGFRAFLT3 | |
| SCHEMBL26944633 | 0.81 | CSF1R (0.40) | MDM2CSF1RPDGFRAIRAK4FLT3 | |
| SCHEMBL21980611 | 0.81 | CSF1R (0.39) | MDM2CSF1RPDGFRAFLT3PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632906-B1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | ABBISKO THERAPEUTICS CO LTD (CN) | 2023-12-13 | — | — | EP | disclosed |
| US-11130762-B2 | Azaaryl derivative, preparation method therefor, and application thereof for use in pharmacy | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2021-09-28 | — | — | US | disclosed |
| US-11130762-B2 | Azaaryl derivative, preparation method therefor, and application thereof for use in pharmacy | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2021-09-28 | — | — | US | disclosed |
| US-20200165254-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2020-05-28 | — | — | US | disclosed |
| US-20200165254-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2020-05-28 | — | — | US | disclosed |
| EP-3632906-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |
| EP-3632906-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165254-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | FAR1, CSF1R, CSF3R | MDM2 1405/4885CSF1R 2/4885PDGFRA 977/4885 |
| US-11130762-B2 | Azaaryl derivative, preparation method therefor, and application thereof for use in pharmacy | FAR1, CSF1R, CSF3R | MDM2 1405/4885CSF1R 2/4885PDGFRA 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.