Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 19/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21813839 | 0.84 | UGT8 (0.71) | UGT8 | |
| SCHEMBL21814022 | 0.84 | UGT8 (0.78) | UGT8 | |
| SCHEMBL21813890 | 0.82 | UGT8 (0.78) | UGT8 | |
| SCHEMBL21813463 | 0.80 | UGT8 (0.52) | UGT8 | |
| SCHEMBL21813440 | 0.79 | UGT8 (0.61) | UGT8 | |
| SCHEMBL21813540 | 0.79 | UGT8 (0.51) | UGT8 | |
| SCHEMBL21813998 | 0.79 | UGT8 (0.66) | UGT8 | |
| SCHEMBL21813379 | 0.78 | UGT8 (0.51) | UGT8 | |
| SCHEMBL21813378 | 0.77 | UGT8 (0.49) | UGT8 | |
| SCHEMBL21814211 | 0.77 | UGT8 (0.52) | UGT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861000-A1 | THIENO[3,2-B]PYRIDINE DERIVATIVES AS UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE | Genzyme Corporation (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020072504-A1 | THIENO[3,2-B]PYRIDINE DERIVATIVES AS UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE | GENZYME CORPORATION (US) | 2020-04-09 | — | — | WO | disclosed |