Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21813589 | 0.93 | UGT8 (0.83) | UGT8 | |
| SCHEMBL21813753 | 0.84 | UGT8 (0.83) | UGT8 | |
| SCHEMBL21862127 | 0.84 | UGT8 (1.00) | UGT8 | |
| Hydrochloric Acid SCHEMBL21814166 | 0.83 | UGT8 (0.98) | UGT8 | |
| SCHEMBL21813857 | 0.82 | UGT8 (0.85) | UGT8 | |
| Hydrochloric Acid SCHEMBL21813650 | 0.81 | UGT8 (0.63) | UGT8 | |
| SCHEMBL21813578 | 0.79 | UGT8 (0.67) | UGT8 | |
| SCHEMBL21813311 | 0.78 | UGT8 (0.82) | UGT8 | |
| SCHEMBL21813543 | 0.78 | UGT8 (0.66) | UGT8 | |
| SCHEMBL21813344 | 0.77 | UGT8 (0.67) | UGT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861000-A1 | THIENO[3,2-B]PYRIDINE DERIVATIVES AS UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE | Genzyme Corporation (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020072504-A1 | THIENO[3,2-B]PYRIDINE DERIVATIVES AS UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE | GENZYME CORPORATION (US) | 2020-04-09 | — | — | WO | disclosed |