Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 19/20 | 0.95 |
| ▸ | ATM | Q13315 | 4/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.51 |
| ▸ | ATR | Q13535 | 2/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748285 | 0.98 | MTOR (0.92) | MTORATMPIK3CAATR | |
| SCHEMBL16748262 | 0.98 | MTOR (0.92) | MTORATMPIK3CAATR | |
| SCHEMBL16748286 | 0.98 | MTOR (1.00) | MTORATMPIK3CAATRPRKDC | |
| SCHEMBL16748143 | 0.98 | MTOR (1.00) | MTORATMPIK3CAATRPRKDC | |
| SCHEMBL16748266 | 0.98 | MTOR (1.00) | MTORATMPIK3CAATRPRKDC | |
| SCHEMBL18091282 | 0.94 | MTOR (0.84) | MTORATMPIK3CAATR | |
| SCHEMBL18157232 | 0.94 | MTOR (0.84) | MTORATMPIK3CAATR | |
| SCHEMBL16748308 | 0.93 | MTOR (0.91) | MTORATMPIK3CAATR | |
| SCHEMBL16748315 | 0.93 | MTOR (0.91) | MTORATMPIK3CAATRPRKDC | |
| SCHEMBL18091301 | 0.92 | MTOR (0.82) | MTORATMPIK3CAATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3072893-B1 | KETONE DERIVATIVES OF IMIDAZOLES, PHARMACEUTICAL COMBINATIONS AND USES THEREOF | BEIJING FORELANDPHARMA CO LTD (CN) | 2020-03-18 | — | — | EP | claimed |