SCHEMBL2183116

SCHEMBL2183116

CCCC[C@@H](N)C(=O)N[C@H](CCCC)C(=O)N[C@@H]([C]=O)CCCNC(=N)N

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.48
NPY1R P25929 6/20 0.48
NPY2R P49146 4/20 0.48
NPY5R Q15761 4/20 0.48
DPP7 Q9UHL4 5/20 0.46
DPP4 P27487 3/20 0.40
DPP8 Q6V1X1 3/20 0.40
DPP9 Q86TI2 3/20 0.40
GNAI3 P08754 1/20 0.39
GNAO1 P09471 1/20 0.39
GNAI1 P63096 1/20 0.39
NOD1 Q9Y239 1/20 0.39
RRM1 P23921 1/20 0.38
SLC15A1 P46059 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2193195 1.00 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL2192111 1.00 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL16468922 1.00 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL6240060 1.00 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL2194311 1.00 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL2195938 0.94 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL2182733 0.94 DPP7 (0.51) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL16468933 0.93 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL19717740 0.89 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RDPP4
SCHEMBL21519849 0.89 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NGLY1, CD44, IAPP NPY4R 567/4885NPY1R 544/4885NPY2R 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.