Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.62 |
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.53 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.51 |
| ▸ | KRAS | P01116 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195872 | 0.94 | DPP4 (0.58) | DPP4DPP3CAPN1CTSBNTSR2 | |
| SCHEMBL29842186 | 0.86 | DPP3 (0.65) | DPP4DPP3KDM4EMEN1LMNA | |
| SCHEMBL30051442 | 0.86 | DPP4 (0.62) | DPP4DPP3SOS1KRASKDM4E | |
| SCHEMBL29963309 | 0.85 | DPP3 (0.64) | DPP4DPP3MEN1KMT2ACAPN1 | |
| SCHEMBL31463314 | 0.84 | DPP4 (0.61) | DPP4DPP3CAPN1CTSB | |
| SCHEMBL29498754 | 0.84 | DPP3 (0.61) | DPP4DPP3KDM4EMEN1LMNA | |
| SCHEMBL31474499 | 0.84 | DPP4 (0.61) | DPP4DPP3KDM4EMEN1LMNA | |
| SCHEMBL30052255 | 0.84 | DPP3 (0.69) | DPP4DPP3MEN1KMT2ATACR1 | |
| SCHEMBL21641795 | 0.84 | DPP4 (0.73) | DPP4DPP3SOS1KRASKDM4E | |
| SCHEMBL6438364 | 0.84 | DPP4 (0.73) | DPP4DPP3SOS1KRASKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | DPP4 525/4885DPP3 332/4885SOS1 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.