SCHEMBL21834450

SCHEMBL21834450

O=C(O)c1ccc(I)cc1.[KH]

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.94
TSHR P16473 3/20 0.67
TP53 P04637 1/20 0.67
SRD5A2 P31213 3/20 0.57
RXRA P19793 1/20 0.57
RXRB P28702 1/20 0.57
CA1 P00915 4/20 0.56
CA2 P00918 4/20 0.56
CA12 O43570 1/20 0.55
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
DAO P14920 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79334 0.97 TPMT (1.00) TPMTTSHRTP53SRD5A2RXRA
Hydrochloric Acid SCHEMBL309608 0.94 TPMT (0.94) TPMTTSHRTP53SRD5A2RXRA
SCHEMBL10612337 0.94 TPMT (0.94) TPMTTSHRTP53SRD5A2RXRA
SCHEMBL10613727 0.94 TPMT (0.94) TPMTTSHRTP53SRD5A2RXRA
SCHEMBL15052170 0.94 TPMT (0.94) TPMTTSHRTP53SRD5A2RXRA
SCHEMBL9316851 0.94 TPMT (0.94) TPMTTSHRTP53SRD5A2RXRA
SCHEMBL9317200 0.94 TPMT (0.94) TPMTTSHRTP53SRD5A2RXRA
Methane SCHEMBL17672827 0.94 TPMT (0.94) TPMTTSHRTP53SRD5A2RXRA
Ethane SCHEMBL5738403 0.92 TPMT (0.90) TPMTTSHRTP53SRD5A2RXRA
SCHEMBL1972646 0.90 TPMT (0.85) TPMTTSHRTP53SRD5A2RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820839-A1 METHOD FOR PREPARATION OF POTASSIUM 5-IODO-2-CARBOXYBENZENE SULFONATE Lonza Solutions AG (CH) 2021-05-19 EP disclosed
WO-2020064753-A1 METHOD FOR PREPARATION OF POTASSIUM 5-IODO-2-CARBOXYBENZENE SULFONATE LONZA LTD (CH) 2020-04-02 WO disclosed