Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260088 | 1.00 | CA4 (0.38) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL28372033 | 0.96 | CA4 (0.38) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL1527764 | 0.96 | CA4 (0.38) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL9548511 | 0.96 | CA4 (0.41) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL9548523 | 0.96 | CA4 (0.41) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL21835150 | 0.85 | SLC22A6 (0.33) | CA4CA2CTH | |
| SCHEMBL9548520 | 0.85 | CA4 (0.33) | CA4CA2CTH | |
| SCHEMBL1527762 | 0.83 | CA4 (0.33) | CA4CTSLCA2FOLH1CTH | |
| SCHEMBL10801435 | 0.83 | CA4 (0.44) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL2916274 | 0.78 | CA4 (0.44) | CA4CTSLCA2FOLH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159598-A1 | POLYPEPTIDE CLEAVAGE METHODS | Absci Corporation | 2023-05-25 | — | — | US | disclosed |
| US-20230072673-A1 | C-PEPTIDES AND PROINSULIN POLYPEPTIDES COMPRISING THE SAME | Absci Corporation | 2023-03-09 | — | — | US | disclosed |
| US-11584785-B2 | C-peptides and proinsulin polypeptides comprising the same | ABSCI, LLC (US) | 2023-02-21 | — | — | US | disclosed |
| EP-3856760-A1 | PROTEIN PURIFICATION METHODS | AbSci, LLC (US) | 2021-08-04 | — | — | EP | disclosed |
| US-20200299343-A1 | C-PEPTIDES AND PROINSULIN POLYPEPTIDES COMPRISING THE SAME | ABSCI LLC (US) | 2020-09-24 | — | — | US | disclosed |
| WO-2020069011-A1 | PROTEIN PURIFICATION METHODS | ABSCI, LLC (US) | 2020-04-02 | — | — | WO | disclosed |