Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLR1A | O95602 | 15/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21836168 | 0.93 | POLR1A (0.54) | POLR1AKMT2AALDH1A1MEN1KCNH2 | |
| SCHEMBL21836155 | 0.92 | POLR1A (0.59) | POLR1AKMT2AALDH1A1MEN1KCNH2 | |
| SCHEMBL21836145 | 0.89 | POLR1A (0.54) | POLR1AKMT2AALDH1A1MEN1KCNH2 | |
| SCHEMBL21836152 | 0.87 | POLR1A (0.53) | POLR1AKMT2AALDH1A1MEN1KCNH2 | |
| SCHEMBL21798881 | 0.86 | POLR1A (0.54) | POLR1AKMT2AALDH1A1MEN1KCNH2 | |
| SCHEMBL21798883 | 0.86 | POLR1A (0.54) | POLR1AKMT2AALDH1A1MEN1KCNH2 | |
| SCHEMBL21836158 | 0.83 | POLR1A (0.55) | POLR1AKMT2AALDH1A1MEN1KCNH2 | |
| SCHEMBL21836131 | 0.81 | POLR1A (0.54) | POLR1AKMT2AALDH1A1MEN1KCNH2 | |
| SCHEMBL21836086 | 0.80 | POLR1A (0.57) | POLR1AKMT2AALDH1A1MEN1 | |
| SCHEMBL21836100 | 0.79 | POLR1A (0.62) | POLR1AKMT2AALDH1A1MEN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632913-A1 | CARBOXYLIC ACID DERIVATIVES OF PYRIDOQUINAZOLINES USEFUL AS PROTEIN KINASE INHIBITORS | Oncostellae, S.L. (ES) | 2020-04-08 | — | — | EP | disclosed |