Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825157 | 1.00 | CHRM1 (0.41) | CHRM1CCR5L3MBTL3L3MBTL1LMNA | |
| SCHEMBL21837251 | 1.00 | CHRM1 (0.41) | CHRM1CCR5L3MBTL3L3MBTL1LMNA | |
| SCHEMBL18825156 | 1.00 | CHRM1 (0.41) | CHRM1CCR5L3MBTL3L3MBTL1LMNA | |
| SCHEMBL21837274 | 0.86 | CHRM1 (0.39) | CHRM1L3MBTL3L3MBTL1LMNACHRM2 | |
| SCHEMBL21837257 | 0.86 | CHRM1 (0.46) | CHRM1L3MBTL3L3MBTL1LMNACHRM2 | |
| SCHEMBL21837272 | 0.86 | CHRM1 (0.39) | CHRM1L3MBTL3L3MBTL1LMNACHRM2 | |
| SCHEMBL21837254 | 0.86 | CHRM1 (0.46) | CHRM1L3MBTL3L3MBTL1LMNACHRM2 | |
| SCHEMBL28225559 | 0.86 | CHRM1 (0.40) | CHRM1CCR5L3MBTL3L3MBTL1LMNA | |
| SCHEMBL18825096 | 0.85 | CHRM1 (0.60) | CHRM1PKMCHRM2CHRM4TP53 | |
| SCHEMBL18849557 | 0.85 | CHRM1 (0.60) | CHRM1PKMCHRM2CHRM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3370828-B1 | OXIME COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | HEPTARES THERAPEUTICS LTD (GB) | 2020-04-15 | — | — | EP | claimed |