Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825283 | 1.00 | CHRM1 (0.42) | CHRM1CHRM2CHRM3CHRM4CCR5 | |
| SCHEMBL18825281 | 1.00 | CHRM1 (0.42) | CHRM1CHRM2CHRM3CHRM4CCR5 | |
| SCHEMBL21837270 | 1.00 | CHRM1 (0.42) | CHRM1CHRM2CHRM3CHRM4CCR5 | |
| SCHEMBL18825110 | 0.91 | CHRM1 (0.43) | CHRM1CHRM2CHRM3CHRM4CCR5 | |
| SCHEMBL21837258 | 0.91 | CHRM1 (0.43) | CHRM1CHRM2CHRM3CHRM4CCR5 | |
| SCHEMBL18825108 | 0.91 | CHRM1 (0.43) | CHRM1CHRM2CHRM3CHRM4CCR5 | |
| SCHEMBL21837273 | 0.91 | CHRM1 (0.43) | CHRM1CHRM2CHRM3CHRM4CCR5 | |
| SCHEMBL18825102 | 0.89 | CHRM1 (0.56) | CHRM1CHRM2CHRM3CHRM4TP53 | |
| SCHEMBL18849552 | 0.89 | CHRM1 (0.56) | CHRM1CHRM2CHRM3CHRM4TP53 | |
| SCHEMBL29854514 | 0.89 | CHRM1 (0.56) | CHRM1CHRM2CHRM3CHRM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3370828-B1 | OXIME COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | HEPTARES THERAPEUTICS LTD (GB) | 2020-04-15 | — | — | EP | claimed |