SCHEMBL218377

SCHEMBL218377

CC[C]1C=Cc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SETD7 Q8WTS6 3/20 0.42
LMNA P02545 6/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPT P10636 5/20 0.41
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 3/20 0.41
KDM4E B2RXH2 3/20 0.41
ALOX15 P16050 2/20 0.41
BCHE P06276 1/20 0.41
POLB P06746 1/20 0.41
PTPRC P08575 1/20 0.41
THRB P10828 1/20 0.41
PKM P14618 1/20 0.41
IDO1 P14902 1/20 0.41
HPGD P15428 1/20 0.41
PTPN1 P18031 1/20 0.41
ACHE P22303 1/20 0.41
CES1 P23141 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20703457 0.98 SETD7 (0.41) SETD7LMNAMEN1KMT2AMAPT
SCHEMBL27707601 0.98 SETD7 (0.41) SETD7LMNAMEN1KMT2AMAPT
SCHEMBL27688569 0.98 SETD7 (0.41) SETD7LMNAMEN1KMT2AMAPT
SCHEMBL28073494 0.98 SETD7 (0.41) SETD7LMNAMEN1KMT2AMAPT
SCHEMBL28073394 0.94 SETD7 (0.39) SETD7LMNAMEN1KMT2AMAPT
SCHEMBL28807007 0.92 SETD7 (0.38) SETD7LMNAMEN1KMT2AMAPT
SCHEMBL27948744 0.92 SETD7 (0.38) SETD7LMNAMEN1KMT2AMAPT
SCHEMBL28806995 0.92 CYP1A2 (0.40) SETD7LMNAMEN1KMT2AMAPT
SCHEMBL27932930 0.92 SETD7 (0.38) SETD7LMNAMEN1KMT2AMAPT
SCHEMBL27948954 0.92 SETD7 (0.38) SETD7LMNAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9447211-B2 Preparation method of catalyst for polyolefin polymerization and preparation method of polyolefin LG CHEM, LTD. (KR) 2016-09-20 US claimed
EP-2837640-B1 METHOD FOR PRODUCING CATALYST FOR POLYOLEFIN POLYMERIZATION AND METHOD FOR PREPARING POLYOLEFIN LG CHEMICAL LTD (KR) 2016-09-07 EP claimed
US-20160152742-A1 PREPARATION METHOD OF CATALYST FOR POLYOLEFIN POLYMERIZATION AND PREPARATION METHOD OF POLYOLEFIN LG CHEM, LTD. (KR) 2016-06-02 US claimed
EP-1910427-B1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2015-05-13 EP claimed
EP-2837640-A1 METHOD FOR PRODUCING CATALYST FOR POLYOLEFIN POLYMERIZATION AND METHOD FOR PREPARING POLYOLEFIN LG Chem, Ltd. (KR) 2015-02-18 EP claimed
US-8822714-B2 More advanced preparation method of organic-transition metal hydride complexes containing aryl group or alkyl group as hydrogen storage materials HANWHA CHEMICAL CORPORATION (KR) 2014-09-02 US claimed
US-20140219911-A1 DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2014-08-07 US claimed
EP-2076551-B1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2014-08-06 EP claimed
US-20130123527-A1 MORE ADVANCED PREPARATION METHOD OF ORGANIC-TRANSITION METAL HYDRIDE COMPLEXES CONTAINING ARYL GROUP OR ALKYL GROUP AS HYDROGEN STORAGE MATERIALS KIM JONG SIK (KR) 2013-05-16 US claimed
US-8399375-B2 Supported metallocene catalyst composition and a process for the preparation of polyolefin using the same SK GLOBAL CHEMICAL CO., LTD. (KR) 2013-03-19 US claimed
EP-1363955-B1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORP (KR) 2008-04-09 EP claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-20070135297-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK CORPORATION (KR) 2007-06-14 US claimed
WO-2007040294-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-04-12 WO claimed
US-20070004586-A1 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins SK CORPORATION (KR) 2007-01-04 US claimed
US-6943225-B2 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2005-09-13 US claimed
WO-2004076502-A1 SUPPORTED MULTINUCLEAR METALLOCENE CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PREPARING THE SAME HONAM PETROCHEMICAL CORPORATION (KR) 2004-09-10 WO claimed
US-20040072677-A1 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2004-04-15 US claimed
EP-1363955-A1 MULTINUCLEAR METALLOCENE CATALYST Honam Petrochemical Corporation (KR) 2003-11-26 EP claimed
WO-2002060964-A1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORPORATION (KR) 2002-08-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123527-A1 MORE ADVANCED PREPARATION METHOD OF ORGANIC-TRANSITION METAL HYDRIDE COMPLEXES CONTAINING ARYL GROUP OR ALKYL GROUP AS HYDROGEN STORAGE MATERIALS H1-10, HDAC10, TIMM10 SETD7 877/4885LMNA 708/4885MEN1 2067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.