Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637611 | 0.86 | KRAS (0.58) | KRASHAVCR2 | |
| SCHEMBL17030835 | 0.81 | KRAS (0.54) | KRASHAVCR2 | |
| SCHEMBL29765795 | 0.81 | KRAS (0.54) | KRASHAVCR2 | |
| SCHEMBL16637103 | 0.80 | KRAS (0.71) | KRAS | |
| SCHEMBL29765891 | 0.80 | KRAS (0.71) | KRAS | |
| SCHEMBL17030814 | 0.72 | KRAS (0.60) | KRAS | |
| SCHEMBL16646997 | 0.70 | KRAS (0.56) | KRAS | |
| SCHEMBL21838269 | 0.70 | KRAS (0.48) | KRAS | |
| SCHEMBL29765925 | 0.68 | KRAS (0.77) | KRAS | |
| SCHEMBL22301631 | 0.67 | KRAS (0.54) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636639-A1 | INHIBITORS OF KRAS G12C | Araxes Pharma LLC (US) | 2020-04-15 | — | — | EP | disclosed |