Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 1.00 |
| ▸ | MAOB | P27338 | 6/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.57 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.57 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880547 | 1.00 | KDM1A (1.00) | KDM1AMAOBMAOACISD1KDM1B | |
| SCHEMBL14881552 | 1.00 | KDM1A (1.00) | KDM1AMAOBMAOACISD1KDM1B | |
| SCHEMBL16394487 | 1.00 | KDM1A (1.00) | KDM1AMAOBMAOACISD1KDM1B | |
| SCHEMBL14880450 | 0.92 | KDM1A (0.84) | KDM1AMAOBMAOACISD1KDM1B | |
| SCHEMBL14880577 | 0.83 | KDM1A (1.00) | KDM1AMAOBMAOACISD1KDM1B | |
| SCHEMBL21841010 | 0.83 | KDM1A (1.00) | KDM1AMAOBMAOACISD1KDM1B | |
| SCHEMBL14881815 | 0.83 | KDM1A (1.00) | KDM1AMAOBMAOACISD1KDM1B | |
| SCHEMBL16394375 | 0.83 | KDM1A (1.00) | KDM1AMAOBMAOACISD1KDM1B | |
| SCHEMBL25069388 | 0.79 | KDM1A (0.71) | KDM1AMAOBMAOACISD1KDM1B | |
| SCHEMBL25069389 | 0.79 | KDM1A (0.71) | KDM1AMAOBMAOACISD1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768805-B1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2020-03-25 | — | — | EP | disclosed |