Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 12/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21845477 | 0.87 | GRIN2B (0.36) | GRIN2BGRIN1OPRK1GRIN2DGRIN3B | |
| SCHEMBL21845610 | 0.86 | PDK2 (0.43) | GRIN2BGRIN1KDM4EPDK2GRIN2D | |
| SCHEMBL21845657 | 0.85 | GRIN2B (0.36) | GRIN2BGRIN1PDK2GRIN2DGRIN3B | |
| SCHEMBL21845624 | 0.85 | GRIN2B (0.38) | GRIN2BGRIN1PDK2 | |
| SCHEMBL21845606 | 0.84 | GRIN2B (0.37) | GRIN2BGRIN1MEN1MAPTKMT2A | |
| SCHEMBL21455604 | 0.84 | GRIN2B (0.43) | GRIN2BGRIN1KDM4EMEN1LMNA | |
| SCHEMBL21845635 | 0.83 | GRIN2B (0.40) | GRIN2BGRIN1MEN1MAPTKMT2A | |
| SCHEMBL19677380 | 0.82 | GRIN2B (0.40) | GRIN2BGRIN1PDK2GRIN2DGRIN3B | |
| SCHEMBL26166960 | 0.78 | GRIN2B (0.46) | GRIN2BGRIN1PDK2GRIN2DGRIN3B | |
| SCHEMBL21230782 | 0.78 | GRIN2D (0.33) | GRIN2BGRIN1PDK2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748878-B1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |