Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21895745 | 0.79 | — | — | |
| SCHEMBL21912187 | 0.76 | KRAS (0.47) | KRAS | |
| SCHEMBL21912059 | 0.72 | — | — | |
| SCHEMBL25020002 | 0.71 | — | — | |
| SCHEMBL21895575 | 0.70 | — | — | |
| SCHEMBL21895637 | 0.69 | KRAS (0.36) | KRAS | |
| SCHEMBL25021552 | 0.69 | CHRNB4 (0.38) | KRAS | |
| SCHEMBL21896266 | 0.69 | — | — | |
| SCHEMBL21895536 | 0.67 | TLR7 (0.38) | KRAS | |
| SCHEMBL21895564 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020055760-A1 | COMBINATION THERAPIES | Mirati Therapeutics, Inc. (US) | 2020-03-19 | — | — | WO | disclosed |