SCHEMBL21847101

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21847138	0.92	BRD4 (0.46)	BRD4BRD2ADORA3TSPOBRD3
	SCHEMBL8320587	0.90	BRD4 (0.45)	BRD4BRD2ADORA3TSPOBRD3
	SCHEMBL21847229	0.88	BRD4 (0.45)	BRD4BRD2ADORA3TSPOBRD3
	SCHEMBL21847104	0.88	PDE4B (0.40)	BRD4CYP1A2CYP3A4CYP2D6CYP2C19
	SCHEMBL8318059	0.85	BRD4 (0.45)	BRD4BRD2ADORA3TSPOBRD3
	SCHEMBL8316217	0.83	BRD4 (0.42)	BRD4BRD2BRD3
	SCHEMBL8317447	0.83	BRD4 (0.42)	BRD4ALDH1A1ADORA3TSPORAB9A
	SCHEMBL8317711	0.83	BRD4 (0.44)	BRD4BRD2ADORA3TSPOBRD3
	SCHEMBL21847207	0.83	BRD4 (0.53)	BRD4BRD2ADORA3TSPOBRD3
	SCHEMBL8316015	0.81	BRD4 (0.51)	BRD4BRD2ADORA3TSPOBRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.