SCHEMBL2184730

SCHEMBL2184730

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CCC(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 7/20 0.64
NPY1R P25929 5/20 0.64
NPY2R P49146 3/20 0.64
FOLH1 Q04609 1/20 0.61
IL1RN P18510 1/20 0.59
ERAP2 Q6P179 1/20 0.59
BACE1 P56817 6/20 0.58
BACE2 Q9Y5Z0 3/20 0.58
NPY5R Q15761 2/20 0.56
NAALAD2 Q9Y3Q0 1/20 0.55
ACE P12821 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30844216 0.96 NPY4R (0.67) NPY4RNPY1RNPY2RFOLH1IL1RN
SCHEMBL29895758 0.94 NPY4R (0.65) NPY4RNPY1RNPY2RFOLH1IL1RN
SCHEMBL2184740 0.92 NPY4R (0.66) NPY4RNPY1RNPY2RFOLH1IL1RN
SCHEMBL29531691 0.91 NPY4R (0.59) NPY4RNPY1RNPY2RFOLH1IL1RN
SCHEMBL30123009 0.91 NAALAD2 (0.61) NPY4RNPY1RNPY2RFOLH1IL1RN
SCHEMBL30905993 0.91 BACE1 (0.61) BACE1BACE2
SCHEMBL31064856 0.91 NAALAD2 (0.66) NPY4RNPY1RNPY2RFOLH1BACE1
SCHEMBL29349540 0.90 NAALAD2 (0.68) NPY4RNPY1RNPY2RFOLH1IL1RN
SCHEMBL29734944 0.90 FOLH1 (0.68) NPY4RNPY1RNPY2RFOLH1IL1RN
SCHEMBL29822390 0.90 FOLH1 (0.68) NPY4RNPY1RNPY2RFOLH1NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497644-B2 Subtilisin variants and their use Fresenius Kabi Ipsum S.R.L. (IT) 2025-12-16 US disclosed
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NGLY1, CD44, IAPP NPY4R 567/4885NPY1R 544/4885NPY2R 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.