Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PPID | Q08752 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735282 | 0.94 | PTPN1 (0.72) | PTPN1TSHRNR1H4EPHX2KMT2A | |
| SCHEMBL274924 | 0.89 | TSHR (0.79) | PTPN1TSHRNR1H4KMT2ANPC1 | |
| SCHEMBL2932295 | 0.84 | PTPN1 (0.73) | PTPN1TSHRNR1H4EPHX2KMT2A | |
| SCHEMBL1253488 | 0.83 | PTPN1 (0.62) | PTPN1TSHRNR1H4EPHX2KMT2A | |
| SCHEMBL13477518 | 0.83 | KMT2A (0.61) | PTPN1NR1H4EPHX2KMT2AHDAC1 | |
| SCHEMBL12133623 | 0.82 | KMT2A (0.76) | PTPN1KMT2AHDAC1HDAC6NPC1 | |
| SCHEMBL25598493 | 0.82 | PTPN1 (0.66) | PTPN1TSHRNR1H4EPHX2KMT2A | |
| SCHEMBL8737881 | 0.81 | TDP1 (0.77) | TSHRNR1H4KMT2ANPC1L3MBTL1 | |
| SCHEMBL11244794 | 0.81 | PTPN1 (0.70) | PTPN1TSHRKMT2ANPC1L3MBTL1 | |
| SCHEMBL18471433 | 0.80 | TSHR (0.67) | PTPN1TSHRNR1H4KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858836-A1 | COMPOUND AND USE THEREOF | Novagenesis Therapeutix (Suzhou) Limited (CN) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020062951-A1 | COMPOUND AND USE THEREOF | 愈磐生物科技（苏州）有限公司 | 2020-04-02 | — | — | WO | disclosed |