Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 19/20 | 0.42 |
| ▸ | ATR | Q13535 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 13/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.35 |
| ▸ | PRKDC | P78527 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21851020 | 0.83 | ATM (0.57) | ATMATRMTORPIK3CAPRKDC | |
| SCHEMBL21850966 | 0.83 | ATM (0.57) | ATMATRMTORPIK3CAPRKDC | |
| SCHEMBL21851017 | 0.83 | ATM (0.57) | ATMATRMTORPIK3CAPRKDC | |
| SCHEMBL21851099 | 0.80 | ATM (0.56) | ATMATRMTORPIK3CA | |
| SCHEMBL24221457 | 0.75 | ATM (0.35) | ATMATRPRKDC | |
| SCHEMBL24221450 | 0.75 | ATM (0.35) | ATMATRPRKDC | |
| SCHEMBL23615854 | 0.72 | ATM (0.57) | ATMATRMTORPIK3CA | |
| SCHEMBL21851127 | 0.72 | ATM (0.57) | ATMATRMTORPIK3CA | |
| SCHEMBL24772825 | 0.71 | ATM (0.42) | ATMATRMTORPIK3CAPRKDC | |
| SCHEMBL29968726 | 0.69 | ATM (0.53) | ATMATRMTORPIK3CAPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020063855-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2020-04-02 | — | — | WO | disclosed |