Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 20/20 | 0.49 |
| ▸ | ATR | Q13535 | 5/20 | 0.49 |
| ▸ | MTOR | P42345 | 17/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24221451 | 0.92 | ATM (0.47) | ATMATRMTORPIK3CAKCNH2 | |
| SCHEMBL21851177 | 0.88 | ATM (0.54) | ATMATRMTORPIK3CAKCNH2 | |
| SCHEMBL21851215 | 0.87 | ATM (0.53) | ATMATRMTORPIK3CAKCNH2 | |
| SCHEMBL21851127 | 0.86 | ATM (0.57) | ATMATRMTORPIK3CAKCNH2 | |
| SCHEMBL23615854 | 0.86 | ATM (0.57) | ATMATRMTORPIK3CAKCNH2 | |
| SCHEMBL21851164 | 0.85 | ATM (0.54) | ATMATRMTORPIK3CAKCNH2 | |
| SCHEMBL21851066 | 0.84 | ATM (0.51) | ATMATRMTORPIK3CAKCNH2 | |
| SCHEMBL21851043 | 0.84 | ATM (0.58) | ATMATRMTORPIK3CAKCNH2 | |
| SCHEMBL21851097 | 0.83 | ATM (0.56) | ATMATRMTORPIK3CAKCNH2 | |
| SCHEMBL29968726 | 0.83 | ATM (0.53) | ATMATRMTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845532-B1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC (CN) | 2022-12-21 | — | — | EP | disclosed |
| US-20210380599-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2021-12-09 | — | — | US | disclosed |
| EP-3845532-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020063855-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2020-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380599-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | ATM, CHEK2, CHEK1 | ATM 1/4885ATR 5/4885MTOR 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.