Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 5/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 3/20 | 0.34 |
| ▸ | TNKS | O95271 | 3/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29969684 | 0.90 | PRKDC (0.49) | PRKDCATMTNKSTNKS2 | |
| SCHEMBL21494360 | 0.90 | PRKDC (0.49) | PRKDCATMTNKSTNKS2 | |
| SCHEMBL21512724 | 0.89 | PRKDC (0.41) | PRKDCIRAK4ATM | |
| SCHEMBL29968406 | 0.89 | PRKDC (0.41) | PRKDCIRAK4ATM | |
| SCHEMBL21851184 | 0.87 | PRKDC (0.38) | PRKDCATM | |
| SCHEMBL29968385 | 0.86 | IRAK4 (0.44) | PRKDCIRAK4ATMTNKSTNKS2 | |
| SCHEMBL29968853 | 0.86 | IRAK4 (0.42) | PRKDCIRAK4ATMPIK3CAMTOR | |
| SCHEMBL21513362 | 0.86 | IRAK4 (0.44) | PRKDCIRAK4ATMTNKSTNKS2 | |
| SCHEMBL26131405 | 0.86 | IRAK4 (0.44) | PRKDCIRAK4ATMTNKSTNKS2 | |
| SCHEMBL26130364 | 0.86 | IRAK4 (0.42) | PRKDCIRAK4ATMPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845532-B1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC (CN) | 2022-12-21 | — | — | EP | disclosed |
| EP-3845532-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020063855-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2020-04-02 | — | — | WO | disclosed |