Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.65 |
| ▸ | CNR1 | P21554 | 7/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186048 | 0.92 | CNR2 (0.73) | CNR2CNR1TDP1 | |
| SCHEMBL2185163 | 0.91 | CNR2 (0.68) | CNR2CNR1TDP1 | |
| SCHEMBL2186076 | 0.91 | CNR2 (0.74) | CNR2CNR1TDP1 | |
| SCHEMBL2186833 | 0.88 | CNR2 (0.72) | CNR2CNR1TDP1 | |
| SCHEMBL2187202 | 0.87 | CNR2 (0.73) | CNR2CNR1TDP1 | |
| SCHEMBL2186051 | 0.85 | CNR2 (0.68) | CNR2CNR1TDP1 | |
| SCHEMBL2185805 | 0.85 | CNR1 (0.63) | CNR2CNR1 | |
| SCHEMBL14746852 | 0.84 | CNR2 (0.77) | CNR2CNR1TDP1 | |
| SCHEMBL2492413 | 0.82 | CNR2 (0.52) | CNR2CNR1 | |
| SCHEMBL16161285 | 0.82 | CNR2 (0.59) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030345-B2 | Tricyclic pyrazole derivatives as cannabinoid receptor modulators | CADILA HEALTHCARE LIMITED (IN) | 2011-10-04 | — | — | US | claimed |
| EP-2343302-A1 | TRICYCLIC PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2011-07-13 | — | — | EP | claimed |
| US-8030345-B2 | Tricyclic pyrazole derivatives as cannabinoid receptor modulators | CADILA HEALTHCARE LIMITED (IN) | 2011-10-04 | — | — | US | disclosed |
| EP-2343302-A1 | TRICYCLIC PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2011-07-13 | — | — | EP | disclosed |