Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 6/20 | 0.56 |
| ▸ | PPP5C | P53041 | 2/20 | 0.56 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.56 |
| ▸ | NPY4R | P50391 | 1/20 | 0.56 |
| ▸ | PPM1B | O75688 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PPP1CC | P36873 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18235539 | 1.00 | TFPI2 (0.56) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL18235534 | 1.00 | TFPI2 (0.56) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL20214915 | 0.88 | PPM1B (0.47) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL18235532 | 0.88 | TFPI2 (0.59) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL20215684 | 0.87 | PPM1B (0.48) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL18235540 | 0.86 | TFPI2 (0.60) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL26377839 | 0.86 | TFPI2 (0.60) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL18073218 | 0.86 | TFPI2 (0.54) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL21851608 | 0.84 | TFPI2 (0.54) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL22642272 | 0.83 | TFPI2 (0.56) | TFPI2PPP5CPPP2CANPY4RPPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3736275-A1 | OXABICYCLOHEPTANE PRODRUGS FOR USE IN TREATING CANCER | Lixte Biotechnology, Inc. (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-3294287-B1 | OXABICYCLOHEPTANE PRODRUGS | LIXTE BIOTECHNOLOGY INC (US) | 2020-04-08 | — | — | EP | disclosed |