Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 11/20 | 0.34 |
| ▸ | FLT3 | P36888 | 4/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21851762 | 0.95 | CSF1R (0.34) | CSF1RFLT3PDGFRAPDGFRBLCK | |
| SCHEMBL21851747 | 0.83 | PIK3C3 (0.38) | CSF1RFLT3PDGFRAPDGFRBLCK | |
| SCHEMBL21824013 | 0.79 | CSF1R (0.53) | CSF1RFLT3PDGFRAPDGFRBLCK | |
| SCHEMBL30673545 | 0.79 | CSF1R (0.36) | CSF1RFLT3PDGFRAPDGFRBLCK | |
| SCHEMBL21824017 | 0.79 | CSF1R (0.36) | CSF1RFLT3PDGFRAPDGFRBLCK | |
| SCHEMBL21851788 | 0.79 | CSF1R (0.35) | CSF1RFLT3PDGFRAPDGFRBLCK | |
| SCHEMBL21824023 | 0.74 | CSF1R (0.54) | CSF1RFLT3PDGFRAPDGFRBLCK | |
| SCHEMBL21824002 | 0.74 | CSF1R (0.36) | CSF1RFLT3PDGFRAPDGFRBLCK | |
| SCHEMBL21824042 | 0.73 | CSF1R (0.37) | CSF1RFLT3PDGFRAPDGFRBLCK | |
| SCHEMBL30673542 | 0.73 | CSF1R (0.37) | CSF1RFLT3PDGFRAPDGFRBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632906-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |