Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.59 |
| ▸ | FLT3 | P36888 | 4/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.56 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21824045 | 0.95 | CSF1R (0.57) | CSF1RFLT3PDGFRAPDGFRBKDR | |
| SCHEMBL16047633 | 0.92 | CSF1R (0.59) | CSF1RFLT3PDGFRAPDGFRBKDR | |
| SCHEMBL16046296 | 0.91 | CSF1R (0.68) | CSF1RFLT3PDGFRAPDGFRBKDR | |
| SCHEMBL16046080 | 0.89 | CSF1R (0.59) | CSF1RFLT3PDGFRAPDGFRBKDR | |
| SCHEMBL16046362 | 0.88 | CSF1R (0.67) | CSF1RFLT3PDGFRAPDGFRBKDR | |
| SCHEMBL21823993 | 0.88 | CSF1R (0.59) | CSF1RFLT3PDGFRAPDGFRBKDR | |
| SCHEMBL21823992 | 0.88 | CSF1R (0.59) | CSF1RFLT3PDGFRAPDGFRBKDR | |
| SCHEMBL16046249 | 0.86 | CSF1R (0.70) | CSF1RFLT3PDGFRAPDGFRBKDR | |
| SCHEMBL16048363 | 0.86 | CSF1R (0.59) | CSF1RFLT3PDGFRAPDGFRBKDR | |
| SCHEMBL16046266 | 0.85 | CSF1R (0.69) | CSF1RFLT3PDGFRAPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632906-B1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | ABBISKO THERAPEUTICS CO LTD (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-3632906-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |