Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21918068 | 0.90 | USP2 (0.43) | USP2SMN1; SMN2TSHRALOX15NR1H2 | |
| SCHEMBL1880398 | 0.88 | USP2 (0.51) | USP2SMN1; SMN2TSHRALOX15NR1H2 | |
| SCHEMBL17143487 | 0.85 | NR1H2 (0.41) | USP2SMN1; SMN2NR1H2HPGDEPHX2 | |
| SCHEMBL345212 | 0.85 | USP2 (0.41) | USP2SMN1; SMN2TSHRALOX15HPGD | |
| SCHEMBL345712 | 0.83 | JAK2 (0.42) | USP2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL12884306 | 0.83 | USP2 (0.47) | USP2SMN1; SMN2TSHRALOX15NR1H2 | |
| SCHEMBL21918070 | 0.82 | USP2 (0.40) | USP2SMN1; SMN2TSHRALOX15NR1H2 | |
| SCHEMBL23070921 | 0.82 | USP2 (0.46) | USP2SMN1; SMN2TSHRALOX15NR1H2 | |
| SCHEMBL3158101 | 0.82 | USP2 (0.46) | USP2SMN1; SMN2TSHRALOX15NR1H2 | |
| SCHEMBL16565814 | 0.82 | USP2 (0.46) | USP2SMN1; SMN2TSHRALOX15NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072656-A1 | IMIDOZOPYRIMIDINE DERIVATIVES | GILEAD SCIENCES, INC. (US) | 2020-04-09 | — | — | WO | disclosed |