Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568174 | 0.86 | CCR1 (0.76) | CCR1CYP3A4KCNH2ADRB1 | |
| SCHEMBL566936 | 0.80 | CCR1 (0.61) | CCR1CYP3A4KCNH2ADRB1 | |
| SCHEMBL567954 | 0.79 | CCR1 (1.00) | CCR1CYP3A4KCNH2ADRB1 | |
| SCHEMBL568285 | 0.79 | CCR1 (1.00) | CCR1CYP3A4KCNH2ADRB1 | |
| SCHEMBL567978 | 0.79 | CCR1 (0.84) | CCR1CYP3A4KCNH2ADRB1 | |
| SCHEMBL568184 | 0.78 | CCR1 (0.89) | CCR1CYP3A4KCNH2ADRB1 | |
| SCHEMBL567742 | 0.78 | CCR1 (0.70) | CCR1CYP3A4KCNH2ADRB1 | |
| SCHEMBL567856 | 0.78 | CCR1 (0.88) | CCR1CYP3A4KCNH2ADRB1 | |
| SCHEMBL568069 | 0.78 | CCR1 (0.80) | CCR1CYP3A4KCNH2ADRB1 | |
| SCHEMBL567342 | 0.78 | CCR1 (0.67) | CCR1CYP3A4KCNH2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346868-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |