SCHEMBL2185376

SCHEMBL2185376

C=C(C)C(=O)O[Si](C(C)C)(C(C)C)C(C)CC

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.37
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2185383 0.96 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL2184912 0.92 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL7143131 0.83 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL1963691 0.83 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL2743983 0.82 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL7626648 0.78 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL28760826 0.78 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL2744490 0.77 TSHR (0.34) TSHRALDH1A1
SCHEMBL7575125 0.75 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL28482630 0.75 TSHR (0.38) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020189414-A1 ANTIFOULING COATING COMPOSITION 日東化成株式会社 2020-09-24 WO disclosed
WO-2020189415-A1 ANTIFOULING COATING COMPOSITION 日東化成株式会社 2020-09-24 WO disclosed
CN-109311284-A Antifouling coat, antifouling substrate and ship is laminated 中国涂料株式会社 2019-02-05 CN disclosed
CN-102171294-B Antifouling coating composition, antifouling coating film formed from the composition, coated object having the coating film on surface, and antifouling treatment method by forming the coating film NITTO KASEI CO LTD 2013-09-18 CN disclosed
CN-102171293-B Antifouling coating composition, antifouling coating film formed from the composition, coated object having the coating film on surface, and method of antifouling by forming the coating film NITTO KASEI CO LTD 2013-09-18 CN disclosed
EP-2360213-B1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM FORMED FROM THE COMPOSITION, COATED OBJECT HAVING THE COATING FILM ON SURFACE, AND METHOD OF ANTIFOULING BY FORMING THE COATING FILM NITTO KASEI CO LTD (JP) 2013-09-11 EP disclosed
EP-2360214-B1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM FORMED USING THE COMPOSITION, COATED ARTICLE HAVING THE COATING FILM ON THE SURFACE, AND ANTIFOULING TREATMENT METHOD TO FORM THE COATING FILM NITTO KASEI CO LTD (JP) 2013-07-17 EP disclosed
CN-102171293-A Antifouling coating composition, antifouling coating film formed from the composition, coated object having the coating film on surface, and method of antifouling by forming the coating film NITTO KASEI CO LTD 2011-08-31 CN disclosed
CN-102171294-A Antifouling coating composition, antifouling coating film formed from the composition, coated object having the coating film on surface, and antifouling treatment method by forming the coating film NITTO KASEI CO LTD 2011-08-31 CN disclosed
EP-2360214-A1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM FORMED USING THE COMPOSITION, COATED ARTICLE HAVING THE COATING FILM ON THE SURFACE, AND ANTIFOULING TREATMENT METHOD TO FORM THE COATING FILM Nitto Kasei Co., Ltd. (JP) 2011-08-24 EP disclosed
EP-2360213-A1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM FORMED FROM THE COMPOSITION, COATED OBJECT HAVING THE COATING FILM ON SURFACE, AND METHOD OF ANTIFOULING BY FORMING THE COATING FILM Nitto Kasei Co., Ltd. (JP) 2011-08-24 EP disclosed
US-7989521-B1 Antifouling coating composition, antifouling coating film formed using the composition, coated article having the coating film on the surface, and antifouling treatment method to form the coating film NITTO KASEI CO., LTD. (JP) 2011-08-02 US disclosed
US-20110172325-A1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM FORMED USING THE COMPOSITION, COATED ARTICLE HAVING THE COATING FILM ON THE SURFACE, AND ANTIFOULING TREATMENT METHOD TO FORM THE COATING FILM NITTO KASEI CO., LTD. (JP) 2011-07-14 US disclosed
US-7977407-B1 Antifouling coating composition, antifouling coating film formed from the composition, coated object having the coating film on surface, and method of antifouling by forming the coating film NITTO KASEI CO., LTD. (JP) 2011-07-12 US disclosed
US-20110166253-A1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM FORMED FROM THE COMPOSITION, COATED OBJECT HAVING THE COATING FILM ON SURFACE, AND METHOD OF ANTIFOULING BY FORMING THE COATING FILM NITTO KASEI CO., LTD. (JP) 2011-07-07 US disclosed