SCHEMBL2185394

SCHEMBL2185394

CC(C)C[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H]([C]=O)CCCCN

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 18/20 0.58
NPY1R P25929 11/20 0.58
NPY5R Q15761 9/20 0.58
NPY2R P49146 7/20 0.58
GNAI3 P08754 1/20 0.39
GNAO1 P09471 1/20 0.39
GNAI1 P63096 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2189528 0.93 NPY4R (0.50) NPY4RNPY1RNPY5RNPY2R
SCHEMBL15263460 0.91 NPY4R (0.48) NPY4RNPY1RNPY5RNPY2RGNAI3
SCHEMBL16468902 0.90 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2R
SCHEMBL28761909 0.90 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RGNAI3
SCHEMBL6470040 0.89 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2R
SCHEMBL16497315 0.89 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30355277 0.88 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2RGNAI3
SCHEMBL30490411 0.88 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29872588 0.88 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29666908 0.88 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NGLY1, CD44, IAPP NPY4R 567/4885NPY1R 544/4885NPY5R 588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.