Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 19/20 | 0.50 |
| ▸ | BCL9 | O00512 | 18/20 | 0.50 |
| ▸ | BCL9L | Q86UU0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23456294 | 0.84 | CTNNB1 (0.58) | CTNNB1BCL9BCL9L | |
| SCHEMBL23456296 | 0.84 | CTNNB1 (0.58) | CTNNB1BCL9BCL9L | |
| SCHEMBL21855132 | 0.82 | PDE4B (0.44) | CTNNB1BCL9POLB | |
| SCHEMBL21855133 | 0.82 | PDE4B (0.44) | CTNNB1BCL9POLB | |
| SCHEMBL23456166 | 0.82 | BCL9 (0.61) | CTNNB1BCL9 | |
| SCHEMBL21855100 | 0.77 | CTNNB1 (0.48) | CTNNB1BCL9BCL9L | |
| SCHEMBL30392056 | 0.74 | CTNNB1 (0.55) | CTNNB1BCL9BCL9L | |
| SCHEMBL19404359 | 0.74 | CTNNB1 (0.55) | CTNNB1BCL9BCL9L | |
| SCHEMBL31205136 | 0.73 | PDE4B (0.46) | CTNNB1BCL9POLB | |
| SCHEMBL21855094 | 0.73 | CTNNB1 (0.47) | CTNNB1BCL9BCL9L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081918-A2 | ΒETA-CATENIN AND B-CELL LYMPHOMA 9 (BCL9) INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |