Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446915 | 0.93 | LRRK2 (1.00) | LRRK2TTK | |
| SCHEMBL24042651 | 0.91 | LRRK2 (0.84) | LRRK2TTK | |
| SCHEMBL21938842 | 0.91 | LRRK2 (0.82) | LRRK2TTK | |
| SCHEMBL26841737 | 0.90 | LRRK2 (0.85) | LRRK2TTK | |
| SCHEMBL7449691 | 0.90 | LRRK2 (1.00) | LRRK2TTK | |
| SCHEMBL21939326 | 0.90 | LRRK2 (0.81) | LRRK2TTK | |
| SCHEMBL12065488 | 0.90 | LRRK2 (1.00) | LRRK2TTK | |
| SCHEMBL26654680 | 0.90 | LRRK2 (0.73) | LRRK2TTK | |
| Hydrochloric Acid SCHEMBL30636066 | 0.90 | LRRK2 (0.84) | LRRK2TTK | |
| SCHEMBL7458732 | 0.90 | LRRK2 (1.00) | LRRK2TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081682-A1 | DEGRADERS OF WILD-TYPE AND MUTANT FORMS OF LRRK2 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |