Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21857245 | 0.93 | PFKFB3 (0.84) | PFKFB3 | |
| SCHEMBL28637364 | 0.92 | PFKFB3 (0.78) | PFKFB3 | |
| SCHEMBL21857353 | 0.91 | PFKFB3 (1.00) | PFKFB3 | |
| SCHEMBL13727073 | 0.91 | PFKFB3 (0.81) | PFKFB3 | |
| SCHEMBL28639666 | 0.91 | PFKFB3 (0.80) | PFKFB3 | |
| SCHEMBL21857120 | 0.91 | PFKFB3 (0.81) | PFKFB3 | |
| SCHEMBL21857247 | 0.91 | PFKFB3 (1.00) | PFKFB3 | |
| SCHEMBL21857595 | 0.90 | PFKFB3 (1.00) | PFKFB3 | |
| SCHEMBL28644721 | 0.89 | PFKFB3 (0.77) | PFKFB3 | |
| SCHEMBL21857150 | 0.89 | PFKFB3 (1.00) | PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020080979-A1 | PFKFB3 INHIBITORS AND THEIR USES | GERO DISCOVERY LIMITED LIABILITY COMPANY (RU) | 2020-04-23 | — | — | WO | disclosed |